Psycho-Genomics Research Institute is a non-profit organization and charity dedicated to research impacts on the experiences and conditions of cancers.
Power Thinking Health Council is a branch of Power Thinking International Incorporated (PTII). PTII is a NSW registered charity, a registered Tax Concession Charity and Deductible Gift Recipient for Australian Tax purposes.
Consultants, sponsors and advisers have included Professor Avni Sali, MBBS PhD FRACS FACS FACNEM, Jan Roberts, Psychologist; Don Power, Power + Executive Coaching; Gayl Chivers Inspirational Life; Charles Sturt University; Gloria Jeans Albury Wodonga; Peard’s Nursery, Albury; Peter Chandler, Chartered Accountant; Albury Wodonga Cancer Support Group; Just Foods Albury, Albury Apartments, Petrea King Quest For Life Centre, Canberra Plan Printing, and over 500 attendees at our workshops and discussion groups.
Make a powerful and positive impact on the experiences and conditions of cancer. Our aim is to install psycho-genomics as a significant field of study and further research to treat and prevent cancers.
Psycho-Genomics Research Institute concentrates on cancer treatment and to establish a treatment which will assist and support currently widely used treatments.
Its importance as an organization is weighed against the high rate of cancer patients worldwide. The worst killer disease affects a lot of people even if they do not contract the disease.
Cancer in Australia
One in three men and one in four women will be directly affected by cancer before the age of 75. In Australia each year, more than 82,000 new cases of cancer are diagnosed. More than half of them will be successfully treated.
The survival rate for many common cancers has increased by more than 30% in the past two decades. But, cancer is still the leading cause of death in Australia, around 34,700 people die from cancer each year.
World wide cancer statistics
6.3 Million people died from cancer
- 3.6 million males and
- 2.7 million females
10.1 Million new cancer cases
22.4 Million living with cancer
By 2020 (Projection)
These World Health Organisation (WHO) projections analysis reveal that every 24 hours another 1,471 people will be diagnosed with a cancer while another 903 will die from cancers in Australia and around the world. Most of these, of course, are loved ones, friends and relatives, care givers, medical practitioners and others affected or influenced by the effects of cancers.
Internationally from a comparative analysis between the years 2000 and 2020 from these WHO cancer projections, all parts of the globe continue to be affected by an increasing incidence and death rate from cancers. Including both men and women, deaths are projected to increase from 10.1 million in 2000 to 15.6 million worldwide in 2020. In North America, from these projections, there will be a 47% increase in cancer deaths between 2000 and 2020, in South America and the Caribbean (78%), Oceania -includes Australia (56%), Northern Europe (24%), Eastern Europe (16%), Western Europe (27%), Southern Europe (20%), Eastern Asia (66%), South Central Asia (72%), South Eastern Asia (76%), Northern Africa and Western Asia (85%) and Dsub-Saharan Africa (65%).
Psycho-Genomics Research Institute believes pathways exist between human psychology, emotions, psychosocial and related environmental impacts, and DNA genes and cancers prognosis and outcomes. These, it believes, are connected and it further believes that urgent research is needed into these links to provide positive opportunities to treat and prevent cancers.
We, at Psycho-Genomics Research Institute, and others across multiple medical disciplines and complementary medical fields, noted over time that there are certain relevant associations and relationships across multiple disciplines and cancer treatments and preventions. These associations and relationships have been identified through our literary review, related research and previously conducted clinical trials.
It is, therefore, establishing this new cancer research front of psycho-genomics. Thus in psycho-genomic treatments and preventions, we would see an integrated approach to seek to prevent and treat cancers, taking into account our psychological, emotional, psychosocial, physiological and genomic pathways.
As most cancers have a genes based diagnosis, we believe it is therefore very important to arrive at treatment and prevention strategies that take into account the pathways through each of these areas and the entire genes pool (genome).
We wish to apply psycho-genomic analysis to an earlier clinical trial that demonstrated positive adjustment and survival outcomes for cancer patients through psychological and psychosocial interventions. The clinical trial interventions included health education (eg cancers, nutrition, exercise, environmental); stress management (eg general stress information, personal stress awareness, relaxation techniques); enhancement of coping skills (eg problem solving, general coping alternatives, theoretical and personal application of solutions); and psychological support (from group members and staff).
Prior experiments and clinical research in related areas, further explored in the article “Stressors, psycho-genomic pathways and cancer”, have:
- provided evidence of longer survivals in groups with cancers such as metastatic breast cancer, 36.6 months versus 18.9 months from the onset of the psychological/psychosocial intervention
- discovered that psychological and psychosocial intervention effects had not entirely disappeared even at the 10 year follow-up in a malignant melanoma clinical trial
- noted that coping through cognitive and behavioural avoidance is detrimental to adjustment
- suggested that anger control and negative affect are not associated with breast cancer, melanoma, or total cancer risk, although they may have a small role in risk of prostate, colorectal and lung cancer
- demonstrated that stress and emotions cannot be separated
- noted different levels of stress and their physiological effects on bodily functions
- provided evidence of a stress-cancer linkage and suggested possible sex differences in the mechanisms of stress-related cancer initiation
- noted that psychosocial factors such as stress, personality, and social support relate to differences in disease progression in cancer patients
- indicated that psychological factors, such as stress, depression, and social support, are able to modulate many of the immunologic activities relevant to patients with malignant disease
- reported that various psychosocial factors, particularly cancer related concerns and depression appear to be related to pre-operative and post operative VEGF level in patients with colorectal cancer
- suggested that when cancer cannot be eradicated, it may be possible to find ways to use the immune system to contain it
- supported a hypothesis that telomere dysfunction impairs chromosomal stability and is associated with an increased risk of various cancers, signalling a possible predisposition gene marker for cancers
- discussed how our mind potentially modulates our genes
- provided information of how gene mutations can affect health and development
- indicated that psychosocial factors, such as social support and distress, are associated with changes in the cellular immune response, not only in peripheral blood, but also at the tumor level. These relationships were more robust in TIL (tumor-infiltrating lymphocytes). These findings support the presence of stress influences in the tumor microenvironment, and
- explored the nature of stressors (environmental) and their epigenetic alterations to the genome on different tissues and organisms.
Currently, the processes for cancer detection consist of screening by physical tests such as PAP tests, mammograms or occult blood faeces. Detection can also consist of the use of blood sampling to detect cancer markers such as Ca125, Ca15-3, CEA or PSA. These screening tests usually occur as minimal symptoms are presented. They may then be followed up by further investigation of abnormalities (body dysfunctions, lesions) and, if cancer is found, treatments, for example, through surgical, radiotherapy, chemotherapy, and complementary medical interventions.
As almost all cancers are gene based, the evidence from earlier research indicates that there is potentially a very positive adjustment and/or survival outcome through psychological/ psychosocial interventions. Positive survival/adjustment outcome, therefore, may be reflective of changes in gene expression and/or gene mutation impacts that reflect on cancer prognosis and outcomes. Thus, in comparison to current cancer screening, identification of abnormalities and treatments, our research will focus on genomics. Our research will include aspects of the complete DNA material, including genes and their functions.
Through its research, the Psycho-Genomics Research Institute aims to:
* identify gene expression and gene mutation marker differentials between cancer and non-cancer population;
* undertake a study over several years looking for blood markers of cellular dysfunctions which predispose to cancer, i.e. a step before the current screening phase, and
* identify psychological/psychosocial intervention affects on those blood markers over time in order to treat cancers to increase survivorship and prevent initiation of cancers.
The Below is a list of Media Releases which are associated with Psycho-Genomics Research Institute. Please click on the titles to read the Media Releases.
"PTHC: Literary Review" - Theo Richter
Date: 21th of January 2008
"Website delves into the mind, health link" - Border Mail
Date: 30th of November 2006
Cancer Researcher happy to be deep in thought - The Weekly Times.
Date: 23rd March 2005
Mind Games: "Can Power Thinking beat cancer?" - The Border Mail.
Section 1 - Section 2 - Section 3
Date: 19th - 20th of June 2004
(Facts and figures, The Cancer Council of Australia)
Psycho-Genomics Research Institute, an Albury, NSW, Australian based non-profit cancer research organization, announces the launch of a new research front it developed to fight cancers, See more on New front to fight cancers. See: 'New Front to Fight Cancers' document
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